The Feline Panleukopenia Virus Antigen Rapid Test is a lateral flow immunochromatographic assay for the qualitative detection of feline Parvovirus antigen (FPV Ag) in cat’s feces or vomit specimen.
Assay Time: 5-10 minutes
Feline panleukopenia virus (FPLV) is a species of parvovirus that can infect all wild and domestic members of the felid (cat) family worldwide. It is a highly contagious, severe infection that causes gastrointestinal, immune system, and nervous system disease. ("Panleukopenia" means a decrease in the number of white blood cells.)
The clinical manifestations of FPLV are variable based on the dose of the virus, the age of the cat, potential breed predispositions, and prior immunity from maternal antibodies, previous exposure, or vaccination. Most infections are subclinical, as evidenced by the high seroprevalence of anti-FPV antibodies among some populations of unvaccinated, healthy cats. The cats that become clinically ill are usually <1 yr old, but older cats are also at risk. There is high mortality in clinically affected kittens and sudden death can occur.
Clinical signs usually develop in 4–6 days after exposure, but can show in 2–14 days. The virus infects and destroys actively dividing cells in bone marrow, lymphoid tissues, intestinal epithelium, and—in very young animals—in the cerebellum and retina. The virus primarily attacks the lining of the gastrointestinal tract, causing internal ulceration and, ultimately, total sloughing of the intestinal epithelium.